Welcome to the Purugganan Laboratory at the Center for Genomics and Systems Biology at New York University. Research in the laboratory is focused on evolutionary, ecological and functional genomics of plants. Active projects in the lab include (1) the Environmental Gene Regulatory Interaction Network (EGRINs) project which aims to characterize gene regulatory networks involved in the rice stress response. (2) There are also multiple active QTL mapping projects in the lab which aim to identify genes controlling variability in salt tolerance among rice varieties. (3) A third major line of research is characterization of the molecular basis of natural variation in Arabidopsis flowering time. (4) Finally, we have an ongoing interest in the process of plant domestication and are currently using whole genome sequencing to understand the origin and diversification of date palm (Phoenix dactylifera) and rice.
The work in the laboratory is funded by the National Science Foundation.
Recent PublicationsRosas U., Mei Y., Xie Q., Banta J.A., Zhou R.W., Seufferheld G., Gerard S., Chou L., Bhambhra N, Parks J.D., Flowers J.M., McClung C.R., Hanzawa Y., Purugganan M.D. 2014. Variation in Arabidopsis flowering time associated with cis-regulatory variation in CONSTANS. Nature Communications 5:3651, doi: 10.1038/ncomms4651
Meyer RS, Purugganan MD. (2013) Evolution of crop species: genetics of domestication and diversification. Nat Rev Genet. 2013 Dec;14(12):840-52. doi: 10.1038/nrg3605
Molina J., Hazzouri K. M., Nickrent D., Geisler M., Meyer R. S., Pentony M. M., Flowers J. M. Pelser P., Barcelona J., Inovejas S. A. Uy I., Yuan W., Wilkins O., Michel C.I., LockLear S., Concepcion G. P. Purugganan M. D. 2014. Possible Loss of the Chloroplast Genome in the Parasitic Flowering Plant Rafflesia lagascae (Rafflesiaceae). Mol. Biol. Evol. 31:793-803
Huang, P., J. Molina, J. M. Flowers, S. A. Jackson, M.D. Purugganan and B. A. Schaal (2012). Phylogeography of Asian wild rice, Oryza rufipogon: A genome-wide view. Mol. Ecol. 21: 4593-4604
Richards, C.L., U. Rosas, J. Banta, N. Bhambhra and M.D. Purugganan (2012). Genome-wide gene expression patterns of Arabidopsis thaliana in nature. PLoS Genetics 8: e1002662.doi:10.1371/journal.pgen.1002662
Banta, J., S. Gerard-Martinez, L. Chou, I. Ehrenreich, A. Wilczek, J. Schmitt and M.D. Purugganan (2012). Climate envelope modeling reveals intraspecific relationships among flowering phenology, niche breadth, and potential range size in Arabidopsis thaliana. Ecol. Letters 15: 769-777.
Samis, K.E. C. J. Murren, O. Bossdorf, K. Donohue, C. B. Fenster, Y. Li, R. L. Malmberg, M. D. Purugganan, J. O. Borevitz, J.R. Stinchcombe (2012). Longitudinal trends in climate drive flowering time clines in North American Arabidopsis thaliana. Ecol. Evolution 2:1162-1180.
Fuller, D.Q., E. Asouti and M.D. Purugganan (2012). Cultivation as slow evolutionary entanglement: Comparative data on rate and sequence of domestication. Vegetation History and Archaeobotany 21:131-145.
Pentony MM, Winters P, Penfold-Brown D, Drew K, Narechania A, Desalle R, Bonneau R, Purugganan MD (2012). The Plant Proteome Folding Project: Structure and Positive Selection in Plant Protein Families. Genome Biol Evol.
Flowers JM, Molina J, Rubinstein S, Huang P, Schaal BA, Purugganan MD (2012). Natural selection in gene-dense regions shapes the genomic pattern of polymorphism in wild and domesticated rice. Mol Biol Evol Feb;29(2):675-87
The main laboratory is located on the 4th floor of the Center for Genomics and Systems Biology, at 12 Waverly Place in the historic neighborhood of Greenwich Village in New York City three blocks east of Washington Square ParkThe nearest subway stops are 8th St. [ N, Q, R, W ] and West 4th St. [A, C, E, B, D, F, V ].
You can find a map of our location here: Map
The lab has recently expanded to include a satellite location at New York University, Abu Dhabi, in the United Arab Emirates. The expansion is part of the new Center for Genomics and Systems Biology at the Center for Science and Engineering in Mussafah, Abu Dhabi. It is staffed full time by a post-doctoral researcher, Khaled Hazzouri
We regularly have open positions for graduate students and post-doctoral researchers in the lab. Please contact us.
Send correspondence by mail to:Department of Biology
1009 Main Building
100 Washington Square East
New York University, New York, NY 10003-6688
office: (212) 992-9628
lab: (212) 998-8465
fax: (212) 995-4015